PicoSearch  
     
CaringBridgeGoodSearch

Fellowships Funded by the
National Niemann-Pick Disease Foundation

(To see a listing of the Research Grants funded by the CCNNPDF/NNPDF, click here.)

(To see a listing of the Clinical Research and Services funded by the CCNNPDF/NNPDF, click here.)

The Canadian Chapter of the National Niemann-Pick Disease Foundation (CCNNPDF) is a sister chapter to the National Niemann-Pick Disease Foundation (NNPDF) (U.S.) and receives administrative support from the NNPDF. Money raised through the CCNNPDF is invested in Niemann-Pick Disease research through the NNPDF's research program with guidance from the NNPDF's Scientific Advisory Board (SAB), Board of Directors, and Research Committee. This partnership helps eliminate redundancy and maximizes the impact of research dollars. (Tammy Vaughan, chair of the CCNNPDF, serves as secretary of the NNPDF, and is on the NNPDF's Research Committee.)


The research funded by the NNPDF is made possible in great part due to the efforts of our NPD families in both the U.S. and Canada, and their extended support network via local community-sponsored events. The NNPDF is truly grateful for this support.

Item #


Date


Researcher


Project

Additional
Information

8 9/2011 -
9/2012

Andrew Munkacsi, Ph.D.
Sponsor: Stephen L. Sturley, Ph.D.
(Columbia University Medical Center;
New York, New York; USA)

Defining the molecular basis of HDAC inhibitors to treat murine, feline, and human models of NPC

$50,000
Jointly sponsored by CCNNPDF & NNPDF

In progress
(Updates to be posted every six months)
7 9/2010 - 9/2013 Dorothea Maetzel, Ph.D..
Sponsor: Rudolf Jaenisch, M.D.
(Whitehead Institute for Biomedical Research; Cambridge, Massachusetts; USA)

In Vitro modelling of Niemann-Pick type C Disease Using Patient-Specific Induced Pluripotent Stem Cells

$100,000
Jointly sponsored by CCNNPDF & NNPDF

Received third year extension of additional $50,000

In progress

Oct 2011 Update

April 2011 Update

Project Summary Sept 2010

6 9/2010 - 9/2013 Nicholas Cianciola, Ph.D.
Sponsor: Cathleen Carlin, Ph.D.
(School of Medicine, Case Western Reserve University; Cleveland, Ohio; USA)

Activation of an alternative cholesterol homeostatic mechanism in NPC

$100,000

Jointly sponsored by CCNNPDF & NNPDF

Received third year extension of additional $50,000

In progress

Oct 2011 Update

April 2011 Update

Project Summary Sept 2010

5 4/2010 -
4/2012
Fabrizio Vacca, Ph.D.
Sponsor: Professor Jean Gruenberg
(University of Geneva, Switzerland)
Analysis of cholesterol export from purified endosomes in NPC cellular models

$100,000
Jointly sponsored by CCNNPDF & NNPDF

In progress

Oct 2011 Update

April 2011
Update


Project Summary Sept 2010

4 9/2009 - 9/2011 Ian Williams, Ph.D.
Sponsor: Professor Fran Platt
(University of Oxford, UK)

Neurobiology of Purkinje Cells in NPC1

$100,000
Jointly sponsored by CCNNPDF & NNPDF


In progress

Oct 2011 Update

April 2011 Update

Project Summary Sept 2010

3

9/15/2004 - 9/14/2006

Nobutaka Ohgami, Ph.D.
Sponsor: T. Y. Chang, Ph.D.
(Dartmouth Medical School; Hanover, New Hampshire; USA)
(2)

Demonstration of NPC1 as a lipid binding protein in Vitro

$80,500
contract modified Jan 2006 to end 31/12/2007


Completed

More Details...

2

3/15/2003 - 3/14/2005

Heng-Ling Liou, Ph.D.
Sponsor: Peter Lobel, Ph.D.
(University of Medicine & Dentistry of New Jersey -Robert Wood Johnson Medical School; Piscataway, New Jersey, USA)
(2 years)

The Role of NPC2 (Niemann-Pick Disease Type C2) Protein in Lysosomal Cholesterol Trafficking

$80,500


Completed

More Details...

1

3/15/2003 - 3/14/2005

Amit Kumar Choudhury, Ph.D.
Sponsor: Richard E. Pagano, Ph.D.
(Mayo Clinic and Foundation; Rochester, Minnesota, USA)
(2 years)

Reduction of Lipid Accumulation in Niemann-Pick Fibroblasts by Modulation of Membrane Trafficking

$80,500


Completed

More Details...

 

“The Canadian Chapter of the National Niemann-Pick Disease Foundation (CCNNPDF) does not engage in the practice of medicine. It is not a medical authority nor does it claim to have medical knowledge. This site is an educational service of the Canadian Chapter of the National Niemann-Pick Disease Foundation and is not meant to provide diagnostic or treatment advice. Information contained or suggested on this Web site does not constitute medical advice. For all information related to care, medication or treatment, the CCNNPDF recommends consulting a physician to determine if information presented is applicable. Please review these additional cautions about medical information provided on the Internet.”